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Nucleofil Skin Boosters

Italian Polynucleotide Science. Bio-Restructuring. Lasting Regeneration.

Nucleofill is a CE-marked range of injectable polynucleotide skin boosters manufactured by Promoitalia, an Italian pharmaceutical company with a strong heritage in advanced aesthetic innovation. Formulated with highly purified, polymerised polynucleotides derived from fish DNA, Nucleofill works by targeting fibroblasts to stimulate collagen and elastin production, improve dermal hydration, and promote deep tissue regeneration without altering facial volume or structure.

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The range includes several targeted formulations at varying polynucleotide concentrations: Nucleofill 20 for facial and hair rejuvenation, Nucleofill 25 for advanced bio-restructuring and lifting of moderate to severe skin laxity, and Nucleofill Eyes for the delicate periorbital area, addressing dark circles, puffiness, and fine lines. Suitable for all skin types, a typical course of 2 to 3 sessions spaced 2 to 4 weeks apart is recommended, with results lasting between 6 and 12 months.

— Why Nucleofil Skin Boosters?

Nucleofil Frequently Asked Questions

What formulations does Nucleofill come in?

Nucleofill is available in several targeted formulations including Nucleofill 20 for facial and hair rejuvenation, Nucleofill 25 for advanced bio-restructuring and lifting of moderate to severe skin laxity, and Nucleofill Eyes specifically formulated for the delicate periorbital area to address dark circles, puffiness, and fine lines.

How does Nucleofill differ from a traditional HA skin booster?

Nucleofill is a polynucleotide-based bio-restructuring injectable rather than a hyaluronic acid skin booster. It works by delivering highly purified polymerised polynucleotides derived from fish DNA directly into the skin to activate fibroblasts, stimulate collagen and elastin production, and promote deep tissue regeneration, improving skin quality from within without adding volume or altering facial structure.

What skin concerns can Nucleofill treat?

Nucleofill is effective for treating fine lines, skin laxity, dehydration, dullness, scarring, pigmentation, and dark circles across the face, neck, décolletage, hands, and scalp. Nucleofill Eyes is specifically formulated for safe use in the periorbital area.

How many sessions are required and how long do results last?

A course of 2 to 3 sessions spaced 2 to 4 weeks apart is recommended for optimal results, with maintenance treatments every 3 to 6 months. Results typically last between 6 and 12 months depending on the formulation used and the individual.

Skin Boosters Knowledge Hub

Aesthetics Wise - Guide to Dermal Fillers for Aesthetic Practitioners - final

Guide to Dermal Fillers for Aesthetic Practitioners

A quick guide to dermal fillers for qualified UK aesthetic practitioners, covering how hyaluronic acid fillers work, key product parameters like G-prime and cohesivity, leading brands, treatment areas, complication management, and UK regulatory requirements.

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