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Plinest Skin Boosters

Italian PN-HPT Technology. Cellular Skin Regeneration.

Plinest is a pioneering range of injectable polynucleotide skin boosters developed by Mastelli Srl, an Italian pharmaceutical manufacturer with over 70 years of experience and more than 100 published clinical studies supporting its formulations. Using proprietary PN-HPT (Polynucleotide High Purification Technology), Plinest delivers highly purified DNA fragments derived from trout to activate fibroblasts, stimulate collagen and elastin production, and promote deep cellular repair and regeneration.

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The range includes several targeted formulations: Plinest for general facial, neck, and décolletage rejuvenation, Plinest Fast for the face, hands, and scalp, Plinest Eye for the delicate periorbital area, and Plinest Hair for scalp rejuvenation and hair thinning. Suitable for all skin types and a broad range of ages, the range is effective for treating fine lines, skin laxity, scarring, pigmentation, and overall loss of skin quality, with a typical course of 3 to 4 sessions spaced 2 to 3 weeks apart and minimal downtime.

— Why Plinest Skin Boosters?

Plinest Skin Frequently Asked Questions

What formulations does Plinest come in?

Plinest is available in several targeted formulations including Plinest for general facial, neck, and décolletage rejuvenation, Plinest Fast for the face, hands, and scalp, Plinest Eye for the delicate periorbital area, and Plinest Hair for scalp rejuvenation and hair thinning treatment.

How does Plinest differ from a traditional HA skin booster?

Plinest is a polynucleotide-based bio-revitaliser rather than a hyaluronic acid skin booster. Using proprietary PN-HPT technology, it delivers highly purified DNA fragments derived from trout directly into the skin to activate fibroblasts and stimulate the skin’s own collagen and elastin production, promoting long-term cellular repair and regeneration rather than surface-level hydration alone.

What skin concerns can Plinest treat?

Plinest is effective for treating fine lines, skin laxity, scarring, pigmentation, dehydration, and overall loss of skin quality across the face, neck, décolletage, hands, and scalp. Plinest Eye is specifically formulated for safe use in the delicate periorbital area.

How many sessions are required and how long do results last?

A typical course of 3 to 4 sessions spaced 2 to 3 weeks apart is recommended, with maintenance treatments every few months to sustain results. Downtime is minimal, with mild redness or swelling at injection sites typically resolving within 24 to 48 hours.

Skin Boosters Knowledge Hub

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